Skin changes over time, with daily routines, and with environmental exposure. At Sesderma, we have spent over three decades researching to understand these changes and develop effective, safe, and tailored solutions for each need.
From this experience, Power of 5 was born, an innovative line of serums that incorporates five derivatives of the same active ingredient in each formula. Thanks to this powerful synergy, we achieve more visible results and greater tolerance, even in the most demanding areas.
Why choose a serum with 5 active ingredients?
In advanced cosmetics, we only talk about a single “star” ingredient. However, the skin doesn’t operate on a single pathway: each molecule has different properties, stability, and penetration capacity. By combining five types of the same active ingredient in one formula, we achieve:
- A more complete and long-lasting action.
- Visible results from the first applications.
- Greater tolerance, avoiding irritation and side effects.
This is the secret of the Power of 5: real effectiveness with maximum safety.
C-VIT 5: serum with 5 types of vitamin C for radiance
Vitamin C is one of the most studied and effective antioxidants in dermocosmetics. It protects against oxidative stress, helps improve skin tone, and restores vitality to dull skin.
Types of vitamin C in cosmetics and their benefits
The 5C Glowing Complex includes derivatives such as ascorbyl glucoside, ethyl ascorbic acid, and magnesium ascorbyl phosphate, each with different absorption levels. Together, they ensure that the skin continuously receives antioxidants, resulting in a more even skin tone and fewer signs of fatigue.
How to use vitamin C in your facial routine
- In the morning: to boost antioxidant protection against pollution and solar radiation.
- Always combined with sunscreen.
RETIAGE 5: serum with 5 types of anti-aging retinoids
Retinol is the quintessential anti-aging active ingredient, but many people abandon it due to the irritation it causes during the first few uses. In RETIAGE 5, the innovation lies in combining five types of next-generation retinoids and encapsulating them using Nanotech, which ensures efficacy with maximum tolerance.
Types of retinoids and how they work on the skin
The 5 Retinoid System integrates retinol, retinal, retinyl, HP retinoate, and sodium retinoyl hyaluronate. This synergy achieves:
- Stimulates collagen synthesis.
- Promotes cell renewal.
- Improves texture and smooths wrinkles.
Retinoids without irritation: the Nanotech advantage
The encapsulation of the active ingredients and their gradual release prevents the usual redness and flaking, allowing even less resistant skin to benefit from retinoids.
HIDRADERM HYAL 5: serum with 5 types of hyaluronic acid
Skin dehydration is one of the main causes of tightness, loss of elasticity, and premature aging. HIDRADERM HYAL 5 combines five forms of hyaluronic acid to hydrate all levels of the skin.
Types of hyaluronic acid and how they hydrate the skin
The 5 H.A. Multilayer Complex integrates high, low, and very low molecular weight hyaluronic acid, as well as hydrolyzed versions and the newest, sodium retinoyl hyaluronate. While the large molecules smooth and protect the surface, the smaller ones penetrate deeply, retaining water and improving elasticity from within.
Benefits of hyaluronic acid for deep hydration
- Multi-layer hydration.
- Plumping effect.
- Reduces transepidermal water loss.
Power of 5 serum efficacy results
Clinical studies have shown visible and measurable improvements:
- C-VIT 5: +78% radiance.*
- RETIAGE 5: +87% softer and smoother skin.**
- HIDRADERM HYAL 5: +97% hydration after just one hour of application.***
* Subjective study conducted on 23 volunteers who applied C-VIT 5 Serum twice daily.
** Subjective evaluation on 30 volunteers who applied RETIAGE 5 Serum once daily for 56 days.
*** Subjective evaluation after 1 hour on 30 volunteers who applied the HIDRADERM HYAL 5 serum.
How to combine the Power of 5 serums in your daily routine
Brightness and hydration routine (dull or tired skin)
- Morning: C-VIT 5 + antioxidant cream + sunscreen.
- Night: Cleansing + HIDRADERM HYAL 5 before night cream.
Anti-aging routine (wrinkles)
- Morning: HIDRADERM HYAL 5 + nourishing cream + sunscreen.
- Night: RETIAGE 5 + night cream night.
Frequently Asked Questions About Vitamin C, Retinoids, and Hyaluronic Acid
Can you combine vitamin C and retinoids in the same routine?
Yes, when these active ingredients are encapsulated in liposomes, they can be included in the same routine. However, if no encapsulation method is used, it’s best to apply them at different times: vitamin C in the morning and retinoids at night.
Do retinoids always irritate the skin?
They don’t have to, but when encapsulation methods aren’t used in their formulation, they can cause a skin reaction during the first few weeks of use. In RETIAGE 5, thanks to Nanotech technology, the skin receives the active ingredients in a gradual and controlled manner, which reduces the likelihood of irritation.
Can hyaluronic acid be used daily?
Yes, even twice a day. It’s a widely used active ingredient and well tolerated by all skin types.
How long does it take to see the results of a facial serum?
With HIDRADERM HYAL 5, hydration is noticeable within one hour*. Radiance and improved firmness are gradually noticeable after several weeks of consistent use.
*Subjective evaluation after 1 hour on 30 volunteers who applied HIDRADERM HYAL 5 serum.
Which serum should I choose based on my skin type?
- Dull skin: C-VIT 5, to provide radiance and evenness.
- Dehydrated skin: HIDRADERM HYAL 5, for multi-layered hydration.
- Wrinkled skin: RETIAGE 5, to improve texture.
Can I combine the three serums?
Yes, always trying to spread out their application to maximize the benefits. For example, C-VIT 5 in the morning, HIDRADERM HYAL 5 at both times, and RETIAGE 5 only at night.
Choose your Power of 5 serum
Brightness, hydration, or anti-aging action. Sesderma’s Power of 5 serums are formulated with a unique synergy of active ingredients encapsulated with Nanotech to achieve visible results with maximum tolerance.
